Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232439 | 0.83 | EGFR (0.48) | TAAR1MAOBEGFRERBB2HCAR2 | |
| SCHEMBL29700723 | 0.81 | SLC7A5 (0.55) | TAAR1MAOBEGFRERBB2ALDH1A1 | |
| SCHEMBL136054 | 0.81 | SLC7A5 (0.55) | TAAR1MAOBEGFRERBB2ALDH1A1 | |
| SCHEMBL2381180 | 0.79 | TSHR (0.56) | KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL788672 | 0.79 | EGFR (0.48) | MAOBEGFRERBB2HCAR2KMT2A | |
| SCHEMBL5240155 | 0.78 | TAAR1 (0.51) | TAAR1RIPK1MAOBEGFRERBB2 | |
| SCHEMBL22849881 | 0.78 | EGFR (0.47) | TAAR1MAOBEGFRERBB2GLS | |
| SCHEMBL2909498 | 0.77 | MAOB (0.48) | RIPK1MAOBEGFRERBB2HCAR2 | |
| SCHEMBL1515805 | 0.76 | TAAR1 (0.46) | TAAR1RIPK1MAOBEGFRERBB2 | |
| SCHEMBL7413003 | 0.76 | SLC7A5 (0.54) | EGFRERBB2HCAR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679436-A | Fused ring heterocycle kinase modulators | SGX PHARMACEUTICALS INC | 2010-03-24 | — | — | CN | disclosed |