Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798202 | 1.00 | KCNN4 (0.45) | KCNN4LMNACYP2D6CYP3A4CYP1A2 | |
| SCHEMBL11137746 | 0.79 | HIF1A (0.47) | KCNN4CYP2D6CYP3A4CYP1A2RECQL | |
| SCHEMBL19791134 | 0.79 | MEN1 (0.37) | LMNAMAPK1ALDH1A1TAAR1HDAC3 | |
| SCHEMBL9711508 | 0.78 | CYP2C19 (0.60) | KCNN4LMNACYP2D6CYP3A4CYP1A2 | |
| SCHEMBL3815914 | 0.78 | KCNN4 (0.46) | KCNN4LMNACYP2D6CYP3A4CYP1A2 | |
| SCHEMBL8285883 | 0.77 | KCNN4 (0.50) | KCNN4LMNACYP2D6CYP3A4CYP1A2 | |
| SCHEMBL10154515 | 0.75 | NPC1 (0.46) | LMNACYP2D6CYP3A4CYP1A2RECQL | |
| SCHEMBL25014080 | 0.75 | KCNN4 (0.48) | KCNN4LMNACYP2D6CYP3A4CYP1A2 | |
| SCHEMBL29086464 | 0.75 | KCNN4 (0.48) | KCNN4LMNACYP2D6CYP3A4CYP1A2 | |
| SCHEMBL28333330 | 0.75 | TAAR1 (0.56) | KCNN4LMNACYP2D6CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101932552-B | Derivatives of 2-amino-2-phenyl-alkanols, preparation thereof and pharmaceutical compositions containing same | OROXCELL | 2014-06-18 | — | — | CN | disclosed |
| CN-101932552-A | Derivatives of 2-amino-2-phenyl-alkanols, preparation thereof and pharmaceutical compositions containing same | OROXCELL | 2010-12-29 | — | — | CN | disclosed |