Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137746 | 0.81 | HIF1A (0.47) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL1144525 | 0.81 | CYP2C19 (0.56) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL27798201 | 0.78 | KCNN4 (0.45) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL27798202 | 0.78 | KCNN4 (0.45) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL13010730 | 0.76 | CYP2C19 (0.50) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL1887928 | 0.76 | CYP2C19 (0.50) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL3655112 | 0.76 | CYP2C19 (0.50) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL5862223 | 0.76 | CYP2C19 (0.54) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL1573515 | 0.76 | CYP2C19 (0.54) | CYP2C19HIF1ACYP3A4CYP1A2RECQL | |
| SCHEMBL31477659 | 0.76 | CYP2C19 (0.54) | CYP2C19HIF1ACYP3A4CYP1A2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |