Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798383 | 0.88 | SCN5A (0.61) | FAAHSCN5ASCN9ASIGMAR1HDAC1 | |
| SCHEMBL27798555 | 0.86 | SCN5A (0.61) | FAAHSCN5ASCN9ASIGMAR1HDAC1 | |
| SCHEMBL2844904 | 0.85 | SCN5A (0.76) | SCN5ASCN9ASIGMAR1HDAC1KDM4E | |
| SCHEMBL16226778 | 0.81 | GAA (0.62) | FAAHHDAC1KDM4EALDH1A1GAA | |
| SCHEMBL27798373 | 0.80 | SCN5A (0.60) | SCN5ASCN9AGAALMNAKMT2A | |
| SCHEMBL27777213 | 0.78 | HTT (0.57) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL2929974 | 0.78 | FAAH (0.72) | FAAHSIGMAR1KDM4EALDH1A1GAA | |
| SCHEMBL27798370 | 0.78 | SCN5A (0.65) | SCN5ASCN9ASIGMAR1HDAC1KDM4E | |
| SCHEMBL6865563 | 0.77 | FAAH (0.61) | FAAHSIGMAR1HDAC1KDM4EALDH1A1 | |
| SCHEMBL27777279 | 0.77 | SCN5A (0.61) | SCN5ASCN9ASIGMAR1HDAC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679220-A | Histone deacetylase inhibitor | METHYLGENE INC | 2010-03-24 | — | — | CN | disclosed |