Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20490279 | 0.95 | HDAC4 (0.58) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL27798435 | 0.89 | HDAC8 (0.51) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL20490192 | 0.83 | HDAC3 (0.54) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL20490369 | 0.83 | HDAC8 (0.54) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL20490177 | 0.81 | HDAC1 (0.58) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL2848220 | 0.81 | HDAC4 (0.58) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL11478601 | 0.80 | NAAA (0.52) | NAAAPLK1EPHX1HTTALDH1A1 | |
| SCHEMBL2847649 | 0.80 | HDAC4 (0.57) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL20490174 | 0.80 | HDAC4 (0.57) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL20490321 | 0.80 | HDAC4 (0.57) | HDAC8HDAC3HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679220-A | Histone deacetylase inhibitor | METHYLGENE INC | 2010-03-24 | — | — | CN | disclosed |