Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196430 | 0.91 | CNR2 (0.57) | CNR2POLBALDH1A1ANPEPTSHR | |
| SCHEMBL2781041 | 0.85 | CNR2 (0.54) | CNR2HDAC2POLBALDH1A1ANPEP | |
| SCHEMBL2781889 | 0.84 | CNR2 (0.54) | CNR2HDAC2POLBOPRM1ALDH1A1 | |
| SCHEMBL2762366 | 0.82 | CNR2 (0.49) | CNR2HDAC2POLBOPRM1ALDH1A1 | |
| SCHEMBL2779752 | 0.79 | CNR2 (0.64) | CNR2POLBALDH1A1ANPEPTSHR | |
| SCHEMBL2783027 | 0.79 | CNR2 (0.64) | CNR2POLBALDH1A1ANPEPTSHR | |
| SCHEMBL13196431 | 0.79 | ANPEP (0.65) | CNR2HDAC2POLBANPEP | |
| SCHEMBL2780605 | 0.79 | CNR2 (0.64) | CNR2HDAC2POLBANPEP | |
| SCHEMBL13196423 | 0.78 | CNR2 (0.63) | CNR2POLBALDH1A1ANPEPTSHR | |
| SCHEMBL13196503 | 0.78 | CNR2 (0.63) | CNR2HDAC2POLBALDH1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | claimed |
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |