Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781245 | 0.90 | CNR2 (0.56) | CNR2ALDH1A1POLBHDAC2ANPEP | |
| SCHEMBL2781057 | 0.88 | CNR2 (0.58) | CNR2OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL2779901 | 0.84 | CNR2 (0.59) | CNR2OPRM1ALDH1A1POLBHDAC2 | |
| SCHEMBL2781009 | 0.83 | CNR2 (0.52) | CNR2OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL13196503 | 0.82 | CNR2 (0.63) | CNR2ALDH1A1POLBHDAC2ANPEP | |
| SCHEMBL2781513 | 0.79 | CNR2 (0.52) | CNR2POLBHDAC2ANPEP | |
| SCHEMBL13196445 | 0.77 | CNR2 (0.57) | CNR2ALDH1A1POLBHDAC2ANPEP | |
| SCHEMBL2780465 | 0.77 | CNR2 (0.51) | CNR2ALDH1A1POLBHDAC2ANPEP | |
| SCHEMBL13196430 | 0.75 | CNR2 (0.57) | CNR2ALDH1A1POLBANPEPLMNA | |
| SCHEMBL2783027 | 0.74 | CNR2 (0.64) | CNR2ALDH1A1POLBANPEPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | claimed |