Ethylene

Ethylene

SCHEMBL27799285

C=C.CC(C)c1cccc(F)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
HDAC4 P56524 3/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
HDAC8 Q9BY41 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MDM4 O15151 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
TYR P14679 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CA5A P35218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179253 0.95 ACHE (0.48) ACHEHDAC4HDAC7HDAC5IDO1
Methoxymethane SCHEMBL28044286 0.89 AOC3 (0.49) ACHEHDAC4HDAC7HDAC5IDO1
SCHEMBL27815591 0.84 HDAC4 (0.43) ACHEHDAC4HDAC7HDAC5IDO1
Ethylene SCHEMBL27975151 0.83 HDAC4 (0.52) HDAC4HDAC8KDM4EMDM4ALDH1A1
SCHEMBL13119197 0.83 TAAR1 (0.53) ACHEHDAC4HDAC8KDM4EMDM4
SCHEMBL28597604 0.82 ACHE (0.44) ACHEHDAC4HDAC7HDAC5IDO1
SCHEMBL792296 0.81 ACHE (0.48) ACHEHDAC4HDAC7HDAC5IDO1
Ammonia Solution, Strong SCHEMBL6000669 0.79 ACHE (0.46) ACHEHDAC4HDAC7HDAC5IDO1
SCHEMBL17591473 0.79 ACHE (0.46) ACHEHDAC4HDAC7HDAC5IDO1
SCHEMBL4702366 0.78 HDAC4 (0.48) ACHEHDAC4HDAC7HDAC5IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101930170-B Substrate etching method TAIWAN SEMICONDUCTOR MFG 2013-01-23 CN claimed
CN-101930170-A Conformal photo-sensitive layer and technology TAIWAN SEMICONDUCTOR MFG 2010-12-29 CN claimed
CN-101930170-B Substrate etching method TAIWAN SEMICONDUCTOR MFG 2013-01-23 CN disclosed
CN-101930170-A Conformal photo-sensitive layer and technology TAIWAN SEMICONDUCTOR MFG 2010-12-29 CN disclosed