Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757900 | 0.94 | EPHX1 (0.44) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL6541881 | 0.92 | EPHX1 (0.52) | MAPTALDH1A1GAAHSD17B10EPHX1 | |
| Hydrochloric Acid SCHEMBL28155166 | 0.92 | EPHX1 (0.43) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL28318233 | 0.90 | SMYD3 (0.43) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL4461493 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNANPSR1EPHX1TSHR | |
| Alcohol SCHEMBL3398638 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL9823358 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL1331989 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL7262 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1GAALMNAHSD17B10 | |
| SCHEMBL12881710 | 0.79 | CHRM1 (0.46) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679273-A | 1-substituted tetrahydroisoquinoline compound | ASTELLAS PHARMA INC | 2010-03-24 | — | — | CN | disclosed |