Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2779957 | 1.00 | SCN4A (0.37) | SCN4APRCPPSMB8DPP4DPP8 | |
| Iodide SCHEMBL2779954 | 0.69 | DPP4 (0.40) | SCN4APSMB8DPP4DPP8DPP9 | |
| Iodide SCHEMBL2779951 | 0.69 | DPP4 (0.40) | SCN4APSMB8DPP4DPP8DPP9 | |
| SCHEMBL21705942 | 0.66 | HDAC8 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3848047 | 0.66 | SCN4A (0.32) | SCN4APRCPPSMB8DPP4TGM2 | |
| SCHEMBL29754343 | 0.61 | — | — | |
| SCHEMBL15810597 | 0.61 | — | — | |
| SCHEMBL5696888 | 0.60 | — | — | |
| SCHEMBL805293 | 0.60 | — | — | |
| SCHEMBL809387 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100116340-A1 | DYE SENSITIZED PHOTOELECTRIC CONVERSION DEVICE AND MANUFACTURING METHOD THEREOF, ELECTRONIC EQUIPMENT, AND SEMICONDUCTOR ELECTRODE AND MANUFACTURING METHOD THEREOF | SONY CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2175516-A1 | COLORING MATTER-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT, PROCESS FOR PRODUCING THE COLORING MATTER-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT, ELECTRONIC EQUIPMENT, SEMICONDUCTOR ELECTRODE, AND PROCESS FOR RPODUCING THE SEMICONDUCTOR ELECTRODE | Sony Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |