Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2779951 | 1.00 | DPP4 (0.40) | DPP4DPP8DPP9SCN4AFAP | |
| Iodide SCHEMBL2779949 | 0.69 | SCN4A (0.37) | DPP4DPP8DPP9SCN4AFAP | |
| Iodide SCHEMBL2779957 | 0.69 | SCN4A (0.37) | DPP4DPP8DPP9SCN4AFAP | |
| SCHEMBL21552116 | 0.66 | DPP4 (0.66) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL11439644 | 0.66 | DPP4 (0.66) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13927601 | 0.66 | SCN4A (0.42) | DPP4DPP8DPP9SCN4AFAP | |
| SCHEMBL27360395 | 0.65 | DPP4 (0.47) | DPP4DPP8DPP9SCN4AFAP | |
| SCHEMBL12286036 | 0.65 | DPP4 (0.48) | DPP4DPP8DPP9SCN4AFAP | |
| SCHEMBL3332858 | 0.65 | DPP4 (0.64) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL488954 | 0.65 | DPP4 (0.64) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100116340-A1 | DYE SENSITIZED PHOTOELECTRIC CONVERSION DEVICE AND MANUFACTURING METHOD THEREOF, ELECTRONIC EQUIPMENT, AND SEMICONDUCTOR ELECTRODE AND MANUFACTURING METHOD THEREOF | SONY CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2175516-A1 | COLORING MATTER-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT, PROCESS FOR PRODUCING THE COLORING MATTER-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT, ELECTRONIC EQUIPMENT, SEMICONDUCTOR ELECTRODE, AND PROCESS FOR RPODUCING THE SEMICONDUCTOR ELECTRODE | Sony Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |