Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.72 |
| ▸ | CA9 | Q16790 | 7/20 | 0.72 |
| ▸ | CA1 | P00915 | 6/20 | 0.72 |
| ▸ | CA5A | P35218 | 5/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.72 |
| ▸ | CA12 | O43570 | 4/20 | 0.72 |
| ▸ | CA3 | P07451 | 3/20 | 0.72 |
| ▸ | CA4 | P22748 | 3/20 | 0.72 |
| ▸ | CA6 | P23280 | 3/20 | 0.72 |
| ▸ | CA7 | P43166 | 3/20 | 0.72 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP10 | P09238 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739955 | 0.86 | CA2 (0.73) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3739959 | 0.86 | CA2 (0.73) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL13012614 | 0.84 | CA2 (0.62) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3737799 | 0.82 | CA2 (0.67) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3737802 | 0.82 | CA2 (0.67) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3733276 | 0.82 | CA2 (0.67) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3733268 | 0.82 | CA2 (0.67) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3735518 | 0.82 | CA2 (0.64) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3735515 | 0.82 | CA2 (0.64) | CA2CA9CA1CA5ACA5B | |
| SCHEMBL3732387 | 0.82 | CA2 (0.65) | CA2CA9CA1CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679318-A | Development of Molecular Imaging Probes for Carbonic Anhydrase-IX Using Linkage Chemistry | SIEMENS MEDICAL SOLUTIONS | 2010-03-24 | — | — | CN | claimed |
| CN-101679318-A | Development of Molecular Imaging Probes for Carbonic Anhydrase-IX Using Linkage Chemistry | SIEMENS MEDICAL SOLUTIONS | 2010-03-24 | — | — | CN | disclosed |