Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723839 | 0.89 | KMT2A (0.54) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL1689760 | 0.87 | CA12 (0.43) | ALDH1A1GAACA12CA1CA9 | |
| SCHEMBL28228415 | 0.84 | ALDH1A1 (0.48) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL879946 | 0.83 | KMT2A (0.45) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL31291935 | 0.82 | KMT2A (0.44) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL1667284 | 0.82 | KMT2A (0.44) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL90358 | 0.81 | KDM4E (0.50) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL1667261 | 0.81 | CASR (0.51) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL22032877 | 0.80 | CA12 (0.39) | KMT2ASMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL3927562 | 0.80 | LCK (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214482-A | Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC | 2013-07-24 | — | — | CN | disclosed |
| CN-101679423-A | Imidazo [1, 2-a ] pyridine compounds as receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC | 2010-03-24 | — | — | CN | disclosed |
| CN-101679422-A | Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC | 2010-03-24 | — | — | CN | disclosed |