Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780354 | 0.92 | POLB (0.45) | POLBALDH1A1CHRM2MEN1KMT2A | |
| SCHEMBL2782990 | 0.92 | POLB (0.40) | POLBALDH1A1CHRM2MEN1KMT2A | |
| SCHEMBL2778659 | 0.88 | ALDH1A1 (0.41) | POLBALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2781623 | 0.87 | POLB (0.42) | POLBALDH1A1CHRM2MEN1KMT2A | |
| SCHEMBL2781360 | 0.82 | ALDH1A1 (0.40) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2780116 | 0.80 | POLB (0.36) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2130806 | 0.79 | EPHX2 (0.49) | POLBALDH1A1MEN1KMT2ACHRM3 | |
| SCHEMBL2130811 | 0.79 | EPHX2 (0.49) | POLBALDH1A1MEN1KMT2ACHRM3 | |
| SCHEMBL2784683 | 0.79 | FFAR1 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL2778748 | 0.76 | OPRL1 (0.37) | ALDH1A1KMT2AL3MBTL1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | claimed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |