Styrene

Styrene

SCHEMBL27800151

C=Cc1ccccc1.C=Cc1ccncc1.c1ccncc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
TSHR P16473 2/20 0.64
CYP11B2 P19099 4/20 0.45
CYP19A1 P11511 3/20 0.45
CYP11B1 P15538 1/20 0.43
MAPT P10636 3/20 0.42
NOTUM Q6P988 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
NAPRT Q6XQN6 1/20 0.41
NPC1 O15118 2/20 0.38
GFER P55789 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
G6PC1 P35575 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 1/20 0.37
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL2417176 0.95 ALDH1A1 (0.55) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL9192273 0.95 ALDH1A1 (0.70) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL2956365 0.95 ALDH1A1 (0.70) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL5179653 0.95 ALDH1A1 (0.70) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL28747695 0.95 ALDH1A1 (0.70) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL30014512 0.95 ALDH1A1 (0.70) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL11490854 0.93 ALDH1A1 (0.67) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL28358776 0.93 ALDH1A1 (0.67) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL28265965 0.93 ALDH1A1 (0.67) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1
Styrene SCHEMBL28032514 0.93 ALDH1A1 (0.67) ALDH1A1TSHRCYP11B2CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101632942-B Metalloporphyrin functional poly 4-vinylpyridine-styrene composite crosslinked microsphere catalyst and preparation method thereof UNIV NORTH CHINA 2010-12-08 CN claimed
CN-101632942-A Metalloporphyrin functional poly 4-vinylpyridine-styrene composite crosslinked microsphere catalyst and preparation method thereof UNIV NORTH CHINA 2010-01-27 CN claimed
CN-101632942-B Metalloporphyrin functional poly 4-vinylpyridine-styrene composite crosslinked microsphere catalyst and preparation method thereof UNIV NORTH CHINA 2010-12-08 CN disclosed
CN-101632942-A Metalloporphyrin functional poly 4-vinylpyridine-styrene composite crosslinked microsphere catalyst and preparation method thereof UNIV NORTH CHINA 2010-01-27 CN disclosed