Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1563435 | 0.98 | PDE4D (0.33) | PDE4DPDE4BPDE4APDE4CBDKRB2 | |
| SCHEMBL1563060 | 0.84 | PDE4D (0.36) | PDE4DPDE4BPDE4APDE4CBDKRB2 | |
| SCHEMBL12016011 | 0.80 | BDKRB2 (0.41) | PDE4DPDE4BPDE4APDE4CBDKRB2 | |
| SCHEMBL2874875 | 0.76 | SLC6A4 (0.40) | — | |
| SCHEMBL1563996 | 0.75 | GAA (0.33) | PDE4DBDKRB2 | |
| Hydrochloric Acid SCHEMBL1565153 | 0.74 | BDKRB2 (0.44) | PDE4DPDE4BPDE4APDE4CBDKRB2 | |
| Hydrochloric Acid SCHEMBL6627836 | 0.73 | GAA (0.32) | PDE4DBDKRB2 | |
| SCHEMBL22554165 | 0.72 | PDE4D (0.35) | PDE4DPDE4BPDE4APDE4CBDKRB2 | |
| SCHEMBL30731074 | 0.72 | PDE4D (0.35) | PDE4DPDE4BPDE4APDE4CBDKRB2 | |
| SCHEMBL1564966 | 0.70 | PDE4D (0.43) | PDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679375-A | 8-oxy-quinoline derivatives as bradykinin b2 receptor modulators | JERINI AG | 2010-03-24 | — | — | CN | disclosed |