Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821747 | 0.81 | HPGD (0.36) | HPGDTSHR | |
| SCHEMBL27800951 | 0.81 | HPGD (0.36) | HPGDTSHR | |
| SCHEMBL27800826 | 0.79 | HPGD (0.37) | HPGDTSHR | |
| SCHEMBL28013917 | 0.76 | HPGD (0.30) | HPGDTSHR | |
| SCHEMBL27800909 | 0.71 | HPGD (0.44) | HPGDTSHRHCAR2LMNA | |
| SCHEMBL27471211 | 0.70 | AOC2 (0.30) | — | |
| SCHEMBL28849900 | 0.69 | — | — | |
| SCHEMBL12162717 | 0.63 | HPGD (0.38) | HPGDTSHR | |
| SCHEMBL1206509 | 0.63 | HPGD (0.56) | HPGDTSHRHCAR2LMNA | |
| SCHEMBL28268579 | 0.63 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101945869-B | Pyrido [2,3-B ] pyrazine-8-substituted compounds and uses thereof | CANCER REC TECH LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-101945869-A | Pyrido [2,3-B ] pyrazine-8-substituted compounds and uses thereof | CANCER REC TECH LTD | 2011-01-12 | — | — | CN | disclosed |