⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210398 | 0.77 | — | — | |
| SCHEMBL8771999 | 0.74 | — | — | |
| SCHEMBL6017119 | 0.73 | — | — | |
| SCHEMBL30722022 | 0.72 | — | — | |
| Bromide SCHEMBL16762436 | 0.72 | — | — | |
| SCHEMBL27532709 | 0.71 | — | — | |
| SCHEMBL9148785 | 0.71 | — | — | |
| SCHEMBL3589907 | 0.70 | — | — | |
| SCHEMBL514392 | 0.70 | — | — | |
| SCHEMBL29173796 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580831-A | GRK2 inhibitors and uses thereof | 索纳塔治疗公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-3313816-B1 | METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE | OMEICOS THERAPEUTICS GMBH (DE) | 2023-05-24 | — | — | EP | disclosed |
| CN-114751920-A | Antitumor compounds | 法马马有限公司 | 2022-07-15 | — | — | CN | disclosed |
| US-20210353569-A1 | Analogs of CYP-Eicosanoids for Use in Treating or Preventing a Disorder Associated with Neovascularization and/or Inflammation | OMEICOS THERAPEUTICS GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| CN-108349880-B | CYP eicosanoid metabolism robust analogs for treatment of cardiac disorders | 奥迈科斯治疗公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20190133976-A1 | METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE | OMEICOS THERAPEUTICS GMBH (DE) | 2019-05-09 | — | — | US | disclosed |
| US-20190117597-A1 | ANALOGS OF CYP-EICOSANOIDS FOR USE IN TREATING OR PREVENTING A DISORDER ASSOCIATED WITH NEOVASCULARIZATION AND/OR INFLAMMATION | MAX DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2019-04-25 | — | — | US | disclosed |
| EP-3435993-A1 | ANALOGS OF CYP-EICOSANOIDS FOR USE IN TREATING OR PREVENTING A DISORDER ASSOCIATED WITH NEOVASCULARIZATION AND/OR INFLAMMATION | OMEICOS Therapeutics GmbH (DE) | 2019-02-06 | — | — | EP | disclosed |
| CN-108349880-A | The steady analog of CYP eicosanoid metabolics for treating heart disease | 奥迈科斯治疗公司 | 2018-07-31 | — | — | CN | disclosed |
| US-20100152465-A1 | Functionalized Ionic Liquids, and Methods of Use Thereof | UNIVERSITY OF SOUTH ALABAMA (US) | 2010-06-17 | — | — | US | disclosed |
| US-20080112866-A1 | Functionalized ionic liquids, and methods of use thereof | UNIVERSITY OF SOUTH ALABAMA (US) | 2008-05-15 | — | — | US | disclosed |
| EP-1556390-A4 | FUNCTIONALIZED IONIC LIQUIDS, AND METHODS OF USE THEREOF | UNIV SOUTH ALABAMA (US) | 2007-12-26 | — | — | EP | disclosed |
| US-7208605-B2 | Functionalized ionic liquids, and methods of use thereof | UNIVERSITY OF SOUTH ALABAMA (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1556390-A2 | FUNCTIONALIZED IONIC LIQUIDS, AND METHODS OF USE THEREOF | University Of South Alabama (US) | 2005-07-27 | — | — | EP | disclosed |
| US-20040035293-A1 | Functionalized ionic liquids, and methods of use thereof | UNIVERSITY OF SOUTH ALABAMA | 2004-02-26 | — | — | US | disclosed |
| WO-2003086605-A2 | FUNCTIONALIZED IONIC LIQUIDS, AND METHODS OF USE THEREOF | UNIVERSITY OF SOUTH ALABAMA (US) | 2003-10-23 | — | — | WO | disclosed |
| US-5455249-A | Antirejection agent, immunosuppressant, fungicide, antitumor agent | WYETH | 1995-10-03 | — | — | US | disclosed |
| US-5391730-A | An immunsuppressantes, antiinflammatory agents, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |