Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 9/20 | 0.51 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775432 | 0.85 | GAA (0.55) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL29662262 | 0.85 | IDO1 (0.54) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL367901 | 0.85 | IDO1 (0.54) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL16774987 | 0.81 | GAA (0.52) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL28790441 | 0.81 | MEN1 (0.53) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL4943635 | 0.81 | GAA (0.59) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL27844894 | 0.80 | GAA (0.49) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL27714659 | 0.78 | MEN1 (0.47) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL6241238 | 0.76 | TRPV1 (0.50) | MEN1GAAKMT2AIDO1POLB | |
| SCHEMBL6852142 | 0.75 | GAA (0.61) | MEN1NPC1GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101945869-B | Pyrido [2,3-B ] pyrazine-8-substituted compounds and uses thereof | CANCER REC TECH LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-102906090-A | 1- (5-tert-butyl-2-phenyl-2H-pyrazol-3-yl) -3- [ 2-fluoro-4- (1-methyl-2-oxo-2, 3-dihydro-1H-imidazo [4,5-B ] pyridin-7-yloxy) -phenyl ] -urea and related compounds and their use in therapy | CANCER REC TECH LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-102333770-A | P38 map kinase inhibitors | RESPIVERT LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101945869-A | Pyrido [2,3-B ] pyrazine-8-substituted compounds and uses thereof | CANCER REC TECH LTD | 2011-01-12 | — | — | CN | disclosed |