Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396852 | 0.84 | ALDH1A1 (0.63) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28775432 | 0.81 | GAA (0.55) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27801232 | 0.81 | MEN1 (0.55) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16774987 | 0.80 | GAA (0.52) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6852142 | 0.80 | GAA (0.61) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6636050 | 0.80 | KDM4E (0.50) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL22989549 | 0.79 | GAA (0.47) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27622622 | 0.79 | P2RX7 (0.58) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL22989775 | 0.78 | GAA (0.46) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1586390 | 0.78 | GAA (0.51) | GAANPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762204-B | Inhibitors of hematopoietic cell kinase (P59-HCK) and their use in the treatment of influenza infections | RESPIVERT LTD | 2014-11-19 | — | — | CN | disclosed |
| CN-102341384-B | P38 map kinase inhibitors | RESPIVERT LTD | 2014-11-12 | — | — | CN | disclosed |
| CN-101945869-B | Pyrido [2,3-B ] pyrazine-8-substituted compounds and uses thereof | CANCER REC TECH LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-102762204-A | Inhibitors of hematopoietic cell kinase (P59-HCK) and their use in the treatment of influenza infections | RESPIVERT LTD | 2012-10-31 | — | — | CN | disclosed |
| CN-102341384-A | P38 map kinase inhibitors | RESPIVERT LTD | 2012-02-01 | — | — | CN | disclosed |
| CN-102333770-A | P38 map kinase inhibitors | RESPIVERT LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101945869-A | Pyrido [2,3-B ] pyrazine-8-substituted compounds and uses thereof | CANCER REC TECH LTD | 2011-01-12 | — | — | CN | disclosed |
| US-20080306260-A1 | Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers | ARCHIMICA GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| CN-1070490-C | Indole derivatives | GLAXO WELLCOME SPA (IT) | 2001-09-05 | — | — | CN | disclosed |
| US-6100289-A | ADMINISTERING AN ANALGESIC AMOUNT OF EXCITATORY AMINO ACID ANTAGONIST TO MAMMAL | GLAXO WELLCOME SPA (IT) | 2000-08-08 | — | — | US | disclosed |
| US-5962496-A | CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO WELLCOME SPA (IT) | 1999-10-05 | — | — | US | disclosed |
| US-5760059-A | ANTAGONISTS OF EXCITATORY AMINO ACIDS, TREATMENT OF NEURODEGENERATIVE DISEASES | GLAXO WELLCOME SPA (IT) | 1998-06-02 | — | — | US | disclosed |
| CN-1133042-A | Indole derivatives as NMDA antagonists | GLAXO SPA (IT) | 1996-10-09 | — | — | CN | disclosed |
| EP-0723541-A1 | INDOLE DERIVATIVES AS NMDA ANTAGONISTS | GLAXO WELLCOME S.p.A. (IT) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010517-A1 | INDOLE DERIVATIVES AS NMDA ANTAGONISTS | GLAXO WELLCOME S.P.A. (IT) | 1995-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306260-A1 | Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers | TST, TAAR1, TSHR | GAA 4492/4885NPC1 2285/4885RAB9A 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.