Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27822144 | 0.87 | TDP1 (0.49) | PARP1KDM4EGAAMEN1KMT2A | |
| SCHEMBL27822121 | 0.84 | PARP1 (0.39) | PARP1KDM4EGAAMEN1MAPT | |
| SCHEMBL27822118 | 0.84 | TDP1 (0.45) | PARP1KDM4EGAATDP1HPGD | |
| SCHEMBL2117610 | 0.79 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL27801393 | 0.76 | PDE10A (0.39) | SMN1; SMN2PARP1KDM4EGAAMEN1 | |
| SCHEMBL27801395 | 0.74 | GSK3B (0.39) | SMN1; SMN2KDM4EGAAMEN1MAPT | |
| SCHEMBL14610935 | 0.74 | CCR1 (0.54) | SMN1; SMN2PARP1KDM4EGAATDP1 | |
| SCHEMBL2496543 | 0.73 | KDM4E (0.57) | SMN1; SMN2PARP1KDM4EGAAMEN1 | |
| SCHEMBL31568905 | 0.73 | KDM4E (0.57) | SMN1; SMN2PARP1KDM4EGAAMEN1 | |
| SCHEMBL2116806 | 0.73 | PTGER4 (0.45) | SMN1; SMN2KDM4EGAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959865-A | Quinolines as farnesyl pyrophosphate synthase inhibitor | NOVARTIS AG | 2011-01-26 | — | — | CN | disclosed |