Malonic Acid

Malonic Acid

SCHEMBL27802153

O=C(O)CC(=O)O.O=[N+]([O-])C(O)c1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GSR P00390 1/20 0.42
LMNA P02545 3/20 0.41
MAPK1 P28482 1/20 0.41
BCAT2 O15382 1/20 0.40
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
MITF O75030 1/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL27818326 0.98 MEN1 (0.41) MEN1KMT2AGSRLMNAMAPK1
SCHEMBL156309 0.88 GSR (0.46) MEN1KMT2AGSRLMNAMAPK1
Benzene SCHEMBL27929647 0.88 GSR (0.46) MEN1KMT2AGSRLMNAMAPK1
SCHEMBL27916936 0.86 GSR (0.44) MEN1KMT2AGSRLMNAMAPK1
Acetone SCHEMBL27946865 0.85 HPGD (0.44) MEN1KMT2AGSRLMNAMAPK1
Methyl Alcohol SCHEMBL7290170 0.84 GSR (0.43) MEN1KMT2AGSRLMNAMAPK1
Glycerin SCHEMBL5168442 0.81 GSR (0.50) MEN1KMT2AGSRLMNAMAPK1
SCHEMBL27951259 0.79 GSR (0.40) KMT2AGSRLMNAMAPK1KDM4E
Dimethyl Sulfoxide SCHEMBL9312674 0.79 GSR (0.40) MEN1KMT2AGSRLMNAMAPK1
Toluene SCHEMBL27929648 0.79 LMNA (0.42) MEN1KMT2AGSRLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-214766968-U Filter equipment is used in production of p nitro benzyl alcohol malonic acid monoester 江西环泰化工有限公司 2021-11-19 CN claimed
CN-214763387-U Vacuum distillation device is used in production of p-nitrobenzyl alcohol malonic acid monoester 江西环泰化工有限公司 2021-11-19 CN claimed
CN-214763883-U Multistage screening and purifying equipment for producing p-nitrobenzyl alcohol malonic acid monoester 江西环泰化工有限公司 2021-11-19 CN claimed
CN-107236407-B Fire-retardant, abrasion performance, artificial leather sense synthetic leather slurry preparation method 福建禾欣中裕新材料有限公司 2019-04-02 CN claimed
CN-108060186-A Biological preparation method of p-nitrobenzyl alcohol malonic acid monoester 台州学院 2018-05-22 CN claimed
CN-107236407-A The preparation method of fire-retardant, abrasion performance, the synthetic leather slurry of artificial leather sense 福建禾欣中裕新材料有限公司 2017-10-10 CN claimed
CN-103540622-B Method for synthesizing p-nitrobenzyl alcohol malonate monoacid ester through enzyme catalysis NANJING TECH UNIVERSITY (CN) 2016-04-13 CN claimed
CN-103059025-B Preparation method of carbapenem bicyclic mother nucleus JINGDEZHEN FUXIANG PHARMACEUTICAL Co.,Ltd. (CN) 2015-11-04 CN claimed
CN-103483202-B Preparation method of magnesium mono-p-nitrobenzyl malonate UNIV NORTH CHINA WATER & RESOU 2015-01-21 CN claimed
CN-103540622-A Method for synthesizing p-nitrobenzyl alcohol malonate monoacid ester through enzyme catalysis NANJING UNIVERSITY OF TECHNOLOGY 2014-01-29 CN claimed
CN-103483202-A Preparation method of magnesium mono-p-nitrobenzyl malonate UNIV NORTH CHINA WATER & RESOU 2014-01-01 CN claimed
CN-103059025-A Preparation method of carbapenem bicyclic parent nucleus JIANGXI FUXIANG PHARMACEUTICAL CO LTD 2013-04-24 CN claimed
CN-101955482-B Method for preparing protected meropenem JINGDEZHEN FUXIANG PHARMACEUTICAL CO LTD 2012-03-21 CN claimed
CN-101955482-A Method for preparing protected meropenem JINGDEZHEN FUXIANG PHARMACEUTICAL CO LTD 2011-01-26 CN claimed
CN-214766968-U Filter equipment is used in production of p nitro benzyl alcohol malonic acid monoester 江西环泰化工有限公司 2021-11-19 CN disclosed
CN-214763387-U Vacuum distillation device is used in production of p-nitrobenzyl alcohol malonic acid monoester 江西环泰化工有限公司 2021-11-19 CN disclosed
CN-214763883-U Multistage screening and purifying equipment for producing p-nitrobenzyl alcohol malonic acid monoester 江西环泰化工有限公司 2021-11-19 CN disclosed
CN-102137865-A Process for the preparation of carbapenem compounds RANBAXY LAB LTD 2011-07-27 CN disclosed
CN-102093407-A Method for preparing intermediate for carbapenem antibiotics NEO DANKONG PHARMACUTICAL CO LTD 2011-06-15 CN disclosed
CN-101955482-A Method for preparing protected meropenem JINGDEZHEN FUXIANG PHARMACEUTICAL CO LTD 2011-01-26 CN disclosed