Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780013 | 0.91 | CNR2 (0.68) | CNR2POLBALDH1A1TSHRANPEP | |
| SCHEMBL13196498 | 0.91 | CNR2 (0.70) | CNR2POLBALDH1A1TSHRANPEP | |
| SCHEMBL2780219 | 0.90 | CNR2 (0.69) | CNR2POLBALDH1A1TSHRANPEP | |
| SCHEMBL2781067 | 0.90 | CNR2 (0.69) | CNR2POLBALDH1A1ANPEPL3MBTL1 | |
| SCHEMBL2780774 | 0.88 | CNR2 (0.66) | CNR2POLBALDH1A1TSHRANPEP | |
| SCHEMBL2781046 | 0.87 | CNR2 (0.68) | CNR2POLBANPEPLMNAL3MBTL1 | |
| SCHEMBL2780330 | 0.86 | CNR2 (0.64) | CNR2POLBALDH1A1ANPEPLMNA | |
| SCHEMBL2781227 | 0.86 | CNR2 (0.67) | CNR2POLBALDH1A1TSHRANPEP | |
| SCHEMBL13274022 | 0.85 | CNR2 (0.74) | CNR2POLBALDH1A1TSHRANPEP | |
| SCHEMBL2779892 | 0.82 | CNR2 (0.59) | CNR2POLBALDH1A1TSHRANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |