Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686781 | 0.98 | — | — | |
| SCHEMBL5924841 | 0.86 | HPGD (0.57) | KDM4EACHEHPGDTSHRHCAR2 | |
| SCHEMBL11122001 | 0.84 | TSHR (0.41) | ACHEHPGDTSHREPHX1ALDH1A1 | |
| SCHEMBL7534754 | 0.82 | EPHX1 (0.61) | ACHEHPGDTSHRHCAR2EPHX1 | |
| SCHEMBL8997419 | 0.82 | EPHX1 (0.61) | ACHEHPGDTSHRHCAR2EPHX1 | |
| SCHEMBL7534806 | 0.82 | EPHX1 (0.61) | ACHEHPGDTSHRHCAR2EPHX1 | |
| SCHEMBL3663445 | 0.82 | EPHX1 (0.61) | ACHEHPGDTSHRHCAR2EPHX1 | |
| SCHEMBL21570869 | 0.80 | TSHR (0.48) | ACHEHPGDTSHREPHX1ALDH1A1 | |
| SCHEMBL35709 | 0.80 | — | — | |
| SCHEMBL21706833 | 0.79 | ACHE (0.32) | ACHEHPGDTSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101970516-A | Process for forming random (meth) acrylate-containing prepolymers | JOHNSON & JOHNSON VISION CARE | 2011-02-09 | — | — | CN | disclosed |