Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491638 | 0.86 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1146640 | 0.84 | PNP (0.40) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6153383 | 0.82 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL23764023 | 0.82 | TLR7 (0.46) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6153440 | 0.81 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL23764021 | 0.78 | ADORA2A (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL23422306 | 0.77 | ADORA2A (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL23422141 | 0.76 | ADORA2A (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7204391 | 0.76 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL2060050 | 0.76 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679433-A | Novel adenine compound | DAINIPPON SUMITOMO PHARMA CO | 2010-03-24 | — | — | CN | disclosed |