Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825625 | 0.86 | HPGD (0.40) | KHKMAPTTSHRHPGDSMN1; SMN2 | |
| SCHEMBL27804971 | 0.79 | CETP (0.36) | KHKTSHRHTR7CYP2D6HRH1 | |
| SCHEMBL27825626 | 0.74 | HPGD (0.45) | MAPTTSHRHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL27804980 | 0.74 | MAPT (0.43) | MAPTTSHRHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL27805014 | 0.73 | MAPT (0.51) | MAPTTSHRHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL28786910 | 0.71 | MAPT (0.47) | MAPTTSHRHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL27804979 | 0.70 | GAA (0.38) | MAPTTSHRALDH1A1GAAHTR7 | |
| SCHEMBL27804988 | 0.70 | HRH1 (0.36) | MAPTTSHRHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL27825623 | 0.68 | CETP (0.36) | MAPTTSHRHPGDALDH1A1GAA | |
| SCHEMBL27967265 | 0.67 | MAPT (0.40) | MAPTTSHRHSD17B10GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |