Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825623 | 0.86 | CETP (0.36) | CETPCYP2D6HRH1KCNH2TSHR | |
| SCHEMBL27804972 | 0.79 | KHK (0.36) | CETPCYP2D6HRH1KCNH2TSHR | |
| SCHEMBL27967265 | 0.79 | MAPT (0.40) | CETPTSHR | |
| SCHEMBL27825633 | 0.77 | CASP1 (0.44) | CETPHTR7 | |
| SCHEMBL1124052 | 0.76 | NPSR1 (0.48) | TSHRNPSR1CYP3A4 | |
| SCHEMBL28786910 | 0.74 | MAPT (0.47) | TSHR | |
| SCHEMBL27825621 | 0.74 | MAPT (0.35) | CETPKCNH2TSHR | |
| SCHEMBL27804977 | 0.73 | PIK3CA (0.48) | — | |
| SCHEMBL27805012 | 0.72 | ALDH1A1 (0.38) | HRH1KCNH2TSHRNPSR1 | |
| SCHEMBL27805094 | 0.72 | NCF1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | claimed |
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | disclosed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |