Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825638 | 0.91 | HSD17B10 (0.44) | HSD17B10ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL1123820 | 0.86 | ALDH1A1 (0.58) | MAPTHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1123997 | 0.86 | ALDH1A1 (0.58) | MAPTHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1123887 | 0.85 | ALDH1A1 (0.53) | MAPTHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1124118 | 0.83 | MAPT (0.55) | MAPTHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27805002 | 0.80 | MAPT (0.36) | MAPTHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1123806 | 0.80 | MAPT (0.63) | MAPTHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1123890 | 0.80 | KDM4E (0.51) | MAPTHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL1123969 | 0.80 | KDM4E (0.51) | MAPTHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL27967258 | 0.79 | KMT2A (0.49) | MAPTHSD17B10ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |