Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 11/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27865417 | 0.77 | ALPL (0.49) | ALPLCA9TP53HCAR3CA12 | |
| SCHEMBL28826572 | 0.73 | TP53 (0.43) | ALPLCA9TP53HCAR3CA12 | |
| SCHEMBL28154526 | 0.72 | ALPL (0.54) | ALPLCA9TP53HCAR3CA12 | |
| SCHEMBL1267225 | 0.69 | MAPK1 (0.79) | ALPLCA9TP53HCAR3CA12 | |
| SCHEMBL6848339 | 0.69 | APP (0.70) | CA9CA12 | |
| SCHEMBL27464512 | 0.69 | ALPL (0.55) | ALPLCA9TP53HCAR3CA12 | |
| SCHEMBL1423106 | 0.69 | — | — | |
| SCHEMBL1815529 | 0.68 | HCAR2 (0.53) | ALPLCA9TP53HCAR3CA12 | |
| SCHEMBL4757203 | 0.68 | MAPK1 (0.61) | ALPLMAPK1 | |
| Hydrochloric Acid SCHEMBL23780332 | 0.67 | ALPL (0.53) | ALPLCA9TP53HCAR3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778851-B | Fused bicyclic pyrimidines | BAYER SCHERING PHARMA AG | 2013-05-08 | — | — | CN | disclosed |
| CN-102317291-A | Fused pyrimidines | BAYER SCHERING PHARMA AG | 2012-01-11 | — | — | CN | disclosed |
| CN-101778851-A | Fused bicyclic pyrimidines | BAYER SCHERING PHARMA AG | 2010-07-14 | — | — | CN | disclosed |