SCHEMBL2780702

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2780593	0.86	PDE4B (0.52)	PDE4BMEN1KMT2APOLBPABPC1
	SCHEMBL2782278	0.85	CSF1R (0.54)	PDE4BMEN1KMT2APOLBPABPC1
	SCHEMBL11393864	0.84	PDE4B (0.56)	PDE4BMEN1KMT2APOLBPABPC1
	SCHEMBL11398304	0.83	CYP3A4 (0.69)	PDE4BMEN1KMT2AALDH1A1CYP3A4
	SCHEMBL11391968	0.81	PDE4B (0.54)	PDE4BMEN1KMT2AALDH1A1CYP3A4
	SCHEMBL30310052	0.81	ALDH1A1 (0.60)	MEN1KMT2APOLBALDH1A1CYP3A4
	Hydrochloric Acid SCHEMBL28429627	0.81	ALDH1A1 (0.58)	MEN1KMT2APOLBALDH1A1CYP3A4
	SCHEMBL2797901	0.80	PDE4B (0.51)	PDE4BMEN1KMT2AALDH1A1CYP3A4
	SCHEMBL2778631	0.78	PDE4B (0.60)	PDE4BMEN1KMT2APOLBPABPC1
	SCHEMBL6796126	0.78	CYP3A4 (0.61)	PDE4BMEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.