Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083189 | 0.85 | APLNR (0.42) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL27807201 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL27842062 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL7192070 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL27647767 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL27807196 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL27919778 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL27938329 | 0.84 | TDP1 (0.50) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL5866373 | 0.82 | TDP1 (0.71) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL220281 | 0.82 | TDP1 (0.71) | TDP1MAOAMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816378-B1 | Glycopeptide antibiotic amide derivatives | LILLY CO ELI (US) | 2002-04-10 | — | — | EP | disclosed |
| US-5919756-A | CHLORORIENTICIN A ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0816378-A1 | Glycopeptide antibiotic amide derivatives | ELI LILLY AND COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |