Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138448 | 0.76 | POLQ (0.36) | MAOBALDH1A1MEN1KMT2A | |
| SCHEMBL10659836 | 0.66 | BCL2 (0.52) | PTPN1DRD2DRD1DRD4DRD5 | |
| Water SCHEMBL11327197 | 0.65 | PTPN1 (0.46) | SLC6A4PTPN1DRD2DRD1DRD4 | |
| SCHEMBL27785349 | 0.64 | ALDH1A1 (0.47) | MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL14135416 | 0.63 | PTPN1 (0.45) | SLC6A4PTPN1DRD2DRD1DRD4 | |
| SCHEMBL27629423 | 0.63 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3165408 | 0.63 | PTPN1 (0.47) | SLC6A4PTPN1DRD2DRD1DRD4 | |
| SCHEMBL29878136 | 0.63 | PTPN1 (0.47) | SLC6A4PTPN1DRD2DRD1DRD4 | |
| SCHEMBL31596156 | 0.63 | HTR2A (0.50) | SLC6A4HTR2AALDH1A1MEN1MAPT | |
| SCHEMBL3636993 | 0.63 | HTR2A (0.50) | SLC6A4HTR2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759598-B | Tetracycline compounds with aminoalkylamidines | SHANDONG XUANZHU MEDICAL TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | disclosed |
| CN-101759598-A | Tetracycline compounds with aminoalkylamidines | SHANDONG XUANZHU PHARM TECH CO | 2010-06-30 | — | — | CN | disclosed |