Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1147215 | 1.00 | — | — | |
| Acetic Acid SCHEMBL2379342 | 0.90 | — | — | |
| Methyl Carbamate SCHEMBL28066680 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNABLMPMP22ALOX15 | |
| SCHEMBL64656 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL230124 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1331136 | 0.82 | — | — | |
| Bromide SCHEMBL27962445 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1332734 | 0.82 | — | — | |
| SCHEMBL6195802 | 0.82 | — | — | |
| Guanidine SCHEMBL28136455 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101794090-B | Electrophtography photosensor and image processing system | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-101713933-B | A mono-layer electronic photographic photoreceptor with positive electricity and an image forming apparatus | KYOCERA MITA CORP | 2013-01-02 | — | — | CN | disclosed |
| CN-101840167-B | Electrophotographic photoreceptor and image forming device | KYOCERA MITA CORP | 2012-12-05 | — | — | CN | disclosed |
| CN-101840167-A | Electrophotographic photoreceptor and image forming device | KYOCERA MITA CORP | 2010-09-22 | — | — | CN | disclosed |
| CN-101794090-A | Electronic photographic photoreceptor and image forming apparatus | KYOCERA MITA CORP | 2010-08-04 | — | — | CN | disclosed |
| CN-101713933-A | A mono-layer electronic photographic photoreceptor with positive electricity and an image forming apparatus | KYOCERA MITA CORP | 2010-05-26 | — | — | CN | disclosed |