Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28784376 | 0.87 | KDM4E (0.62) | KDM4EGAALMNAMAPTPOLB | |
| SCHEMBL3638613 | 0.86 | PDE5A (0.65) | KDM4EGAALMNAMAPTPOLB | |
| Chlorobenzene SCHEMBL27786584 | 0.86 | KDM4E (0.61) | KDM4EGAALMNAMAPTPOLB | |
| SCHEMBL3642691 | 0.84 | HRH4 (0.66) | KDM4EGAALMNAMAPTPOLB | |
| SCHEMBL3645747 | 0.84 | APP (0.65) | KDM4EGAALMNAMAPTPOLB | |
| Hydrochloric Acid SCHEMBL3641028 | 0.84 | HRH4 (0.65) | KDM4EGAALMNAMAPTPOLB | |
| SCHEMBL3644257 | 0.83 | PDE5A (0.60) | KDM4EGAALMNAMAPTPOLB | |
| Hydrochloric Acid SCHEMBL3640596 | 0.83 | APP (0.64) | KDM4EGAALMNAMAPTPOLB | |
| SCHEMBL24627394 | 0.82 | HRH4 (0.62) | KDM4EGAALMNAMAPTPOLB | |
| SCHEMBL3639965 | 0.80 | HRH4 (0.60) | KDM4EGAALMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784276-A | Use of compounds for the preparation of antituberculosis agents | SUMMIT CORP PLC | 2010-07-21 | — | — | CN | claimed |
| CN-101784276-A | Use of compounds for the preparation of antituberculosis agents | SUMMIT CORP PLC | 2010-07-21 | — | — | CN | disclosed |