SCHEMBL2780899

SCHEMBL2780899

C=CC(=O)OC[Si](OC(C)=O)(OC(C)=O)OC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.44
HPGD P15428 1/20 0.42
ALDH1A1 P00352 6/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
THRB P10828 2/20 0.36
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5395142 0.82 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5406656 0.82 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2778856 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL106615 0.79 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1276044 0.78 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2778831 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL109189 0.76 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL395305 0.76 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
Propane SCHEMBL28679287 0.76 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9715050 0.74 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107407885-B Silicone composition for printing plate, lithographic printing plate precursor, lithographic printing plate, and method for producing printed matter 东丽株式会社 2020-09-25 CN disclosed
EP-3276417-B1 SILICONE COMPOSITION FOR PRINTING PLATES, LITHOGRAPHIC PRINTING PLATE MASTER, LITHOGRAPHIC PRINTING PLATE AND METHOD OF PRODUCING PRINTED MATTER TORAY INDUSTRIES (JP) 2019-07-17 EP disclosed
US-20190099995-A1 SILICONE COMPOSITION FOR PRINTING PLATES, LITHOGRAPHIC PRINTING PLATE MASTER, LITHOGRAPHIC PRINTING PLATE AND METHOD OF PRODUCING PRINTED MATTER TORAY INDUSTRIES, INC. (JP) 2019-04-04 US disclosed
EP-3276417-A1 SILICONE COMPOSITION FOR PRINTING PLATES, LITHOGRAPHIC PRINTING PLATE MASTER, LITHOGRAPHIC PRINTING PLATE AND METHOD OF PRODUCING PRINTED MATTER Toray Industries, Inc. (JP) 2018-01-31 EP disclosed
CN-107407885-A Galley silicon-ketone composition, original edition of lithographic printing plate, the manufacture method of lithographic plate and printed article 东丽株式会社 2017-11-28 CN disclosed
WO-2010064746-A1 FILM COMPOSITION APM INC. (KR) 2010-06-10 WO disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed