SCHEMBL109189

SCHEMBL109189

C=CC(=O)OC[Si](OCC)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 7/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 2/20 0.42
THRB P10828 4/20 0.40
HCAR2 Q8TDS4 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL28656089 0.98 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27989322 0.91 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL108947 0.91 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL106210 0.91 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4440961 0.90 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27997314 0.86 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL237274 0.85 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3964618 0.83 HCAR2 (0.48) ALDH1A1HSD17B10HCAR2NPSR1LMNA
SCHEMBL105934 0.82 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL108961 0.82 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 914 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108561636-B Wear-resistant composite pipe and preparation method thereof 临海伟星新型建材有限公司 2024-04-30 CN claimed
CN-115960359-B Organosilicon treating agent, preparation method thereof and powder containing organosilicon treating agent 广州硅碳新材料有限公司 2024-02-23 CN claimed
CN-117402545-A Polyurethane/acrylic ester primer and preparation method thereof 黎明化工研究设计院有限责任公司 2024-01-16 CN claimed
CN-117050311-A Photosensitive hyperbranched organic silicon resin and preparation method and application thereof 南京大学 2023-11-14 CN claimed
CN-115960359-A Organic silicon treating agent, preparation method thereof and powder containing organic silicon treating agent 广州硅碳新材料有限公司 2023-04-14 CN claimed
CN-115746616-A Surface-modified hollow silica particles and surface-modified hollow silica dispersion 凯斯科技股份有限公司 2023-03-07 CN claimed
EP-4077524-A1 REACTIVE RESIN COMPONENT, REACTIVE RESIN SYSTEM CONTAINING SAME AND USE THEREOF Hilti Aktiengesellschaft (LI) 2022-10-26 EP claimed
CN-108329638-B Modified high-wear-resistance pipeline material and preparation method thereof 浙江伟星新型建材股份有限公司 2020-07-24 CN claimed
CN-110183176-A A kind of high-strength transparent cement based composites and preparation method thereof 湖南辰砾新材料有限公司 2019-08-30 CN claimed
CN-108329836-A A kind of organic siliconresin that rosin resin is modified 枞阳县三金颜料有限责任公司 2018-07-27 CN claimed
WO-2010112106-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS AG (DE) 2010-10-07 WO claimed
EP-2136933-A1 METHOD FOR IMPRINT LITHOGRAPHY UTILIZING AN ADHESION PRIMER LAYER MOLECULAR IMPRINTS, INC. (US) 2009-12-30 EP claimed
WO-2008127835-A1 METHOD FOR IMPRINT LITHOGRAPHY UTILIZING AN ADHESION PRIMER LAYER MOLECULAR IMPRINTS, INC. (US) 2008-10-23 WO claimed
US-20070212494-A1 Method for Imprint Lithography Utilizing an Adhesion Primer Layer MOLECULAR IMPRINTS, INC. (US) 2007-09-13 US claimed
US-6908723-B2 Photo-patternable mono-phase fluorinated organometallic sol-gels for integrated optics and methods of fabrication NP PHOTONICS, INC. (US) 2005-06-21 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-20040033309-A1 Photo-patternable mono-phase fluorinated organometallic sol-gels for integrated optics and methods of fabrication NP PHOTONICS, INC. 2004-02-19 US claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
US-5580679-A METAL CAP SEALED WITH A POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1996-12-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885HPGD 1893/4885ALDH1A1 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.