Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 6/20 | 0.39 |
| ▸ | ADK | P55263 | 5/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555531 | 0.78 | APP (0.57) | ALDH1A1ALOX15TSHRHSD17B10SNCA | |
| SCHEMBL2188836 | 0.78 | APP (0.57) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| SCHEMBL770159 | 0.78 | ALDH1A1 (0.65) | ALDH1A1ALOX15TSHRHSD17B10SNCA | |
| SCHEMBL10300053 | 0.78 | ALDH1A1 (0.65) | ALDH1A1ALOX15TSHRHSD17B10SNCA | |
| SCHEMBL5496752 | 0.77 | TSHR (0.46) | ALDH1A1TSHRMAPTAPP | |
| SCHEMBL5495027 | 0.76 | APP (0.47) | ALDH1A1ALOX15HSD17B10MAPTAPP | |
| SCHEMBL5492434 | 0.76 | MAPT (0.59) | ALDH1A1HSD17B10MAPTAPPADK | |
| SCHEMBL2539548 | 0.76 | APP (0.37) | MAPTAPPGRM5 | |
| SCHEMBL2545694 | 0.76 | APP (0.37) | MAPTAPP | |
| SCHEMBL4268626 | 0.76 | APP (0.37) | MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046601-A | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R TECH UENO LTD | 2011-05-04 | — | — | CN | disclosed |