Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.31 |
| ▸ | GRM6 | O15303 | 4/20 | 0.31 |
| ▸ | GRM8 | O00222 | 3/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375048 | 0.86 | GRM2 (0.35) | KMT2AGRM2GRM5GRM1GRM4 | |
| SCHEMBL6813803 | 0.81 | GRM2 (0.30) | GRM2GRM5GRM1 | |
| SCHEMBL3369422 | 0.81 | GRM2 (0.36) | GRM2GRM5GRM1GRM4GRM6 | |
| SCHEMBL13757812 | 0.81 | GRM2 (0.36) | GRM2GRM5GRM1GRM4GRM6 | |
| Hydrochloric Acid SCHEMBL3375949 | 0.79 | GRM2 (0.35) | GRM2GRM5GRM1GRM4GRM6 | |
| SCHEMBL14592183 | 0.78 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL25660668 | 0.74 | GRM2 (0.59) | GRM2GRM5GRM1GRM4GRM6 | |
| SCHEMBL27555679 | 0.74 | GRM2 (0.32) | GRM2GRM5GRM1 | |
| SCHEMBL28747535 | 0.71 | ARG1 (0.35) | ALDH1A1GRM2GRM5GRM1CPB2 | |
| SCHEMBL29681754 | 0.71 | ARG1 (0.35) | ALDH1A1GRM2GRM5GRM1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801925-A | antiviral compounds | GILEAD SCIENCES INC | 2010-08-11 | — | — | CN | disclosed |