Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.42 |
| ▸ | CETP | P11597 | 8/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787139 | 0.92 | CETP (0.42) | FDFT1CETPPTGESALDH1A1MAPT | |
| SCHEMBL3089145 | 0.90 | PPARG (0.46) | CETPPTGESALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3084077 | 0.84 | CETP (0.43) | CETPALDH1A1L3MBTL1PPARGPPARA | |
| SCHEMBL27787119 | 0.83 | CYP4F2 (0.49) | PTGESALOX5 | |
| SCHEMBL3093099 | 0.78 | CHRM2 (0.43) | PTGESALDH1A1MAPT | |
| SCHEMBL3079647 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX5 | |
| SCHEMBL3103221 | 0.77 | CYP1A2 (0.45) | PTGESALDH1A1PPARGPPARAALOX5 | |
| SCHEMBL27787093 | 0.76 | BCHE (0.53) | L3MBTL1PPARGPPARAALOX5 | |
| SCHEMBL3097030 | 0.76 | SCN9A (0.40) | FDFT1CETPALDH1A1MAPTPPARG | |
| SCHEMBL3097023 | 0.76 | SCN9A (0.40) | FDFT1CETPALDH1A1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-B | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |