Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 3/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997377 | 0.91 | POLB (0.53) | NAMPTPOLBKMT2ACYP19A1CYP17A1 | |
| SCHEMBL21652695 | 0.87 | MGAM (0.62) | GAAMGAMSIMGAM2PPID | |
| SCHEMBL9867427 | 0.84 | POLB (0.47) | NAMPTTSHRPOLBKMT2ACYP19A1 | |
| SCHEMBL6443516 | 0.84 | NAMPT (0.49) | NAMPTPOLBKMT2ACYP19A1CYP17A1 | |
| SCHEMBL28997380 | 0.82 | POLB (0.53) | NAMPTGAAPOLBKMT2ACYP19A1 | |
| SCHEMBL1557559 | 0.82 | ALDH1A1 (0.61) | GAAMGAMSIMGAM2PPID | |
| SCHEMBL1617976 | 0.81 | CYP19A1 (0.49) | NAMPTGAAMGAMSIMGAM2 | |
| SCHEMBL19308459 | 0.81 | NAMPT (0.47) | NAMPTPOLBKMT2ACYP19A1CYP17A1 | |
| SCHEMBL304656 | 0.80 | CYP19A1 (0.63) | NAMPTPPIDTSHRCYP19A1MAPT | |
| SCHEMBL19439087 | 0.79 | PPID (0.57) | GAAMGAMSIMGAM2PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-B | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |