Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750579 | 0.76 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL3751151 | 0.75 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3765077 | 0.75 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL3758881 | 0.74 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL2055972 | 0.72 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL3754262 | 0.68 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3733359 | 0.68 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3747994 | 0.67 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3723835 | 0.67 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL3758443 | 0.66 | CRHR1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981031-A | Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them | TAKEDA PHARMACEUTICAL | 2011-02-23 | — | — | CN | disclosed |