Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721975 | 0.81 | DGAT1 (0.44) | DGAT1ALDH1A1TSHRCA1CA2 | |
| SCHEMBL1486198 | 0.81 | DGAT1 (0.44) | DGAT1ALDH1A1TSHRCA1CA2 | |
| SCHEMBL27859821 | 0.81 | DGAT1 (0.44) | DGAT1ALDH1A1TSHRCA1CA2 | |
| SCHEMBL28535462 | 0.76 | DGAT1 (0.44) | DGAT1ALDH1A1TSHR | |
| SCHEMBL27482953 | 0.76 | DGAT1 (0.44) | DGAT1ALDH1A1TSHR | |
| SCHEMBL617762 | 0.74 | DGAT1 (0.43) | DGAT1ALDH1A1TSHR | |
| SCHEMBL2141984 | 0.73 | DGAT1 (0.41) | DGAT1ALDH1A1TSHR | |
| SCHEMBL27771798 | 0.73 | DGAT1 (0.41) | DGAT1ALDH1A1TSHR | |
| SCHEMBL27615784 | 0.73 | DGAT1 (0.41) | DGAT1ALDH1A1TSHR | |
| SCHEMBL6687359 | 0.72 | DGAT1 (0.50) | DGAT1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801965-B | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-101801965-A | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-08-11 | — | — | CN | disclosed |