Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778799 | 1.00 | MME (0.56) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2780274 | 0.92 | MME (0.60) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2781125 | 0.92 | MME (0.60) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL11148829 | 0.81 | MME (0.57) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2779649 | 0.81 | MME (0.48) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2777728 | 0.81 | ITGB1 (0.50) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL6170513 | 0.80 | ACE (0.57) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL503474 | 0.80 | ACE (0.57) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL22190054 | 0.79 | KMT2A (0.53) | KMT2AFFAR1FFAR4PPARAPPARG | |
| SCHEMBL22190053 | 0.79 | KMT2A (0.53) | KMT2AFFAR1FFAR4PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258681-B1 | Aromatic Derivatives as HIV Aspartyl Protease Inhibitors | TAIMED BIOLOG INC (TW) | 2012-09-26 | — | — | EP | disclosed |
| EP-2258680-A2 | Aromatic derivatives as HIV aspartyl protease inhibitors | Ambrilia Biopharma Inc. (CA) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258681-A2 | Aromatic Derivatives as HIV Aspartyl Protease Inhibitors | Ambrilia Biopharma Inc. (CA) | 2010-12-08 | — | — | EP | disclosed |
| US-6632816-B1 | Aromatic derivatives as HIV aspartyl protease inhibitors | PHARMACOR INC. (CA) | 2003-10-14 | — | — | US | disclosed |