Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780274 | 0.87 | MME (0.60) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2781125 | 0.87 | MME (0.60) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2781114 | 0.81 | MME (0.56) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2778799 | 0.81 | MME (0.56) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL3006752 | 0.79 | CTSS (0.55) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL2780885 | 0.76 | MME (0.60) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL25258099 | 0.75 | ITGB2 (0.43) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL6170513 | 0.75 | ACE (0.57) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL25295022 | 0.75 | ITGB2 (0.43) | MMEACECPA1ACE2KMT2A | |
| SCHEMBL503474 | 0.75 | ACE (0.57) | MMEACECPA1ACE2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258681-B1 | Aromatic Derivatives as HIV Aspartyl Protease Inhibitors | TAIMED BIOLOG INC (TW) | 2012-09-26 | — | — | EP | disclosed |
| EP-2258680-A2 | Aromatic derivatives as HIV aspartyl protease inhibitors | Ambrilia Biopharma Inc. (CA) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258681-A2 | Aromatic Derivatives as HIV Aspartyl Protease Inhibitors | Ambrilia Biopharma Inc. (CA) | 2010-12-08 | — | — | EP | disclosed |
| WO-2010088608-A2 | SYSTEMS AND METHODS FOR BLOCK-LEVEL MANAGEMENT OF TIERED STORAGE | ATRATO, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| US-20100199036-A1 | SYSTEMS AND METHODS FOR BLOCK-LEVEL MANAGEMENT OF TIERED STORAGE | ATRATO, INC. (US) | 2010-08-05 | — | — | US | disclosed |
| EP-1575914-A1 | AROMATIC DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Procyon Biopharma Inc. (CA) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056764-A1 | AROMATIC DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PROCYON BIOPHARMA INC. (CA) | 2004-07-08 | — | — | WO | disclosed |
| US-6632816-B1 | Aromatic derivatives as HIV aspartyl protease inhibitors | PHARMACOR INC. (CA) | 2003-10-14 | — | — | US | disclosed |