Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19244915 | 1.00 | ACHE (0.57) | ACHEBCHENPC1SMN1; SMN2MAPT | |
| SCHEMBL3061782 | 0.84 | NR1H4 (0.78) | NPC1SMN1; SMN2MAPTNFKB1NFKB2 | |
| SCHEMBL15706789 | 0.84 | NR1H4 (0.71) | NPC1SMN1; SMN2MAPTNFKB1NFKB2 | |
| SCHEMBL2062609 | 0.84 | NR1H4 (0.78) | NPC1SMN1; SMN2MAPTNFKB1NFKB2 | |
| SCHEMBL29936924 | 0.84 | NR1H4 (0.71) | ACHEBCHENPC1SMN1; SMN2MAPT | |
| SCHEMBL16592554 | 0.84 | NR1H4 (0.78) | ACHEBCHENPC1SMN1; SMN2MAPT | |
| SCHEMBL11323465 | 0.84 | NR1H4 (0.78) | ACHEBCHENPC1SMN1; SMN2MAPT | |
| SCHEMBL12270961 | 0.83 | NPC1 (0.54) | NPC1SMN1; SMN2MAPTNFKB1NFKB2 | |
| SCHEMBL16592595 | 0.82 | ACHE (0.57) | ACHEBCHENPC1SMN1; SMN2MAPT | |
| SCHEMBL29147530 | 0.82 | NPC1 (0.72) | ACHEBCHENPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102086177-B | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | HUASHAN HOSPITAL FUDAN UNIV | 2012-07-04 | — | — | CN | claimed |
| CN-102086177-A | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | UNIV FUDAN AF HUASHAN HOSPITAL | 2011-06-08 | — | — | CN | claimed |
| CN-102086177-B | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | HUASHAN HOSPITAL FUDAN UNIV | 2012-07-04 | — | — | CN | disclosed |
| CN-102086177-B | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | HUASHAN HOSPITAL FUDAN UNIV | 2012-07-04 | — | — | CN | disclosed |
| CN-102086177-B | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | HUASHAN HOSPITAL FUDAN UNIV | 2012-07-04 | — | — | CN | disclosed |
| CN-102086177-A | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | UNIV FUDAN AF HUASHAN HOSPITAL | 2011-06-08 | — | — | CN | disclosed |
| CN-102086177-A | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | UNIV FUDAN AF HUASHAN HOSPITAL | 2011-06-08 | — | — | CN | disclosed |
| CN-102086177-A | Method for preparing 4-(3-(4-hydroxylphenyl)-1,2,4-oxadiazole-5-yl)-aniline | UNIV FUDAN AF HUASHAN HOSPITAL | 2011-06-08 | — | — | CN | disclosed |