SCHEMBL27816977

SCHEMBL27816977

N=C(N)Nc1ccc(C(=O)OS(=O)(=O)Cc2ccc3cc(C(=N)N)ccc3c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PLAU P00749 18/20 0.55
▸ PLG P00747 8/20 0.55
▸ KLKB1 P03952 8/20 0.55
▸ PRSS1 P07477 8/20 0.55
▸ F2 P00734 7/20 0.55
▸ PLAT P00750 6/20 0.55
▸ KLK1 P06870 2/20 0.45
▸ FTO Q9C0B1 1/20 0.42
▸ C1R P00736 1/20 0.40
▸ F10 P00742 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10922460 0.86 PLAU (0.54) PLAUPLGKLKB1PRSS1F2
SCHEMBL7347944 0.82 PLAU (0.44) PLAUPLGKLKB1PRSS1F2
SCHEMBL7338130 0.82 MAPT (0.48) PLAUPLGKLKB1PRSS1F2
SCHEMBL10938176 0.80 PLAU (0.48) PLAUPLGKLKB1PRSS1F2
SCHEMBL7343617 0.80 PLAU (0.50) PLAUPRSS1F2F10
SCHEMBL10915437 0.79 F2 (0.44) PLAUPLGKLKB1PRSS1F2
SCHEMBL7562644 0.79 PLAU (0.40) PLAUPLGKLKB1PRSS1F2
Hydrochloric Acid SCHEMBL7565399 0.78 PLAU (0.39) PLAUPLGKLKB1PRSS1F2
SCHEMBL7339823 0.78 PLAU (0.52) PLAUPLGF2PLATKLK1
SCHEMBL10917873 0.77 PLAU (0.46) PLAUPLGKLKB1PRSS1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101868511-A Chemical mechanical polishing solution for polycrystalline silicon ANJI MICROELECTRONICS SHANGHA 2010-10-20 — — CN claimed
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