Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 14/20 | 0.40 |
| ▸ | PLG | P00747 | 10/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.40 |
| ▸ | PLAT | P00750 | 8/20 | 0.40 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.40 |
| ▸ | KLK1 | P06870 | 5/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7565399 | 0.99 | PLAU (0.39) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL7562640 | 0.80 | FTO (0.46) | PLAUPLGPRSS1PLATF2 | |
| Hydrochloric Acid SCHEMBL7565395 | 0.80 | FTO (0.45) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL27816977 | 0.79 | PLAU (0.55) | PLAUPLGPRSS1PLATF2 | |
| Hydrochloric Acid SCHEMBL7564878 | 0.74 | PRSS1 (0.44) | PLAUPLGPRSS1PLATF2 | |
| Hydrochloric Acid SCHEMBL7562340 | 0.73 | FTO (0.46) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL7562958 | 0.71 | F12 (0.45) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL7562225 | 0.71 | FTO (0.46) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL7564449 | 0.70 | FTO (0.45) | PLAUPLGPRSS1PLATF2 | |
| Hydrochloric Acid SCHEMBL7561887 | 0.70 | F12 (0.44) | PLAUPLGPRSS1PLATF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802179-B1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO LTD (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5885990-A | FIBRINOLYSIS PROMOTING ACTION; THROMBOLYSIS ACTION | TORII PHARMACEUTICAL CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0802179-A1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO., LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |