Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393282 | 0.80 | KDM4E (0.82) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL1276481 | 0.80 | KDM4E (0.82) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL27613811 | 0.79 | KDM4E (0.70) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL6130342 | 0.78 | ALDH1A1 (0.68) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL27933369 | 0.78 | KDM4E (0.77) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL23069091 | 0.76 | KDM4E (0.87) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL331600 | 0.76 | NPC1 (0.69) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL29613373 | 0.76 | KDM4E (0.87) | KDM4EMAPTGAARAB9ACYP1A2 | |
| SCHEMBL27796351 | 0.76 | KMT2A (0.62) | KDM4EMAPTRAB9ANPC1POLB | |
| SCHEMBL11868635 | 0.75 | KDM4E (0.69) | KDM4EMAPTGAARAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | claimed |
| CN-101880246-B | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-03 | — | — | CN | disclosed |
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | disclosed |