Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12983470 | 0.90 | TSHR (0.46) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL28280842 | 0.88 | TSHR (0.53) | TSHRHPGDALDH1A1MAPTCA1 | |
| SCHEMBL7909171 | 0.82 | TSHR (0.45) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL31462487 | 0.81 | TSHR (0.50) | TSHRHPGDALDH1A1MAPTATM | |
| SCHEMBL15111700 | 0.79 | CA2 (0.53) | TSHRHPGDCA1CA2ATM | |
| SCHEMBL28185181 | 0.78 | TSHR (0.47) | TSHRHPGDALDH1A1ATMCYP3A4 | |
| SCHEMBL5712789 | 0.78 | TSHR (0.42) | TSHRHPGDMAPTATMHCAR2 | |
| SCHEMBL27816827 | 0.77 | TSHR (0.44) | TSHRHPGDALDH1A1CA1CA2 | |
| SCHEMBL8460582 | 0.77 | TSHR (0.38) | TSHRHPGDALDH1A1ATMCYP3A4 | |
| SCHEMBL11871263 | 0.76 | ZDHHC7 (0.43) | TSHRHPGDMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101835846-A | Silicone hydrogels with amino surface groups | BAUSCH & LOMB | 2010-09-15 | — | — | CN | claimed |
| CN-101835846-A | Silicone hydrogels with amino surface groups | BAUSCH & LOMB | 2010-09-15 | — | — | CN | disclosed |