Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.73 |
| ▸ | HTR1D | P28221 | 20/20 | 0.73 |
| ▸ | HTR1B | P28222 | 20/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 20/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688283 | 0.87 | HTR1A (0.55) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL431334 | 0.85 | HTR1A (0.98) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL426947 | 0.84 | HTR1A (0.98) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL429349 | 0.84 | HTR1A (0.98) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL10212132 | 0.84 | HTR1A (1.00) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL10212143 | 0.83 | HTR1A (1.00) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL10212177 | 0.83 | HTR1A (1.00) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL4182287 | 0.82 | HTR1D (0.98) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL4182250 | 0.81 | HTR1D (1.00) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL432344 | 0.81 | HTR1A (0.98) | HTR1AHTR1DHTR1BSLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048414-B | Fused tricyclic derivatives for the treatment of psychotic disorders | GLAXO GROUP LTD | 2011-09-07 | — | — | CN | disclosed |